Vandelanotte, C., Trost, S., Hodgetts, D., Imam, T., Rashid, M. M., To, Q. G., & Maher, C. (2025). MoveMentor—examining the effectiveness of a machine learning and app-based digital assistant to increase physical activity in adults: protocol for a randomised controlled trial. Trials, 26(1), 233.
[Open Access] https://link.springer.com/article/10.1186/s13063-025-08926-3
Abstract
Physical inactivity is prevalent, leading to a high burden of disease and large healthcare costs. Thus, there is a need for affordable, effective and scalable interventions. However, interventions that are affordable and scalable are beset with modest effects and engagement. Interventions that integrate machine learning with real-time data to offer unprecedented levels of personalisation and customisation might offer solutions. The aim of this study is to conduct a randomised controlled trial to evaluate the effectiveness of a machine learning and app-based digital assistant to increase physical activity.
One hundred and ninety-eight participants will be recruited through Facebook advertisements and randomly allocated to an intervention or control group. Intervention participants will gain access to an app-based physical activity digital assistant that can learn and adapt in real-time to achieve high levels of personalisation and user engagement by virtue of applying a range of machine learning techniques (i.e. reinforcement learning, natural language processing and large language models). The digital assistant will interact with participants in 3 main ways:(1) educational conversations about physical activity; (2) just-in-time personalised in-app notifications (‘nudges’), cues to action encouraging physical activity and (3) chat-based questions and answers about physical activity. Additionally, the app includes adaptive goal setting and an action planning tool. The control group will gain access to the intervention after the last assessment. Outcomes will be measured at baseline, 3 and 6 months. The primary outcome
is device-measured (Axivity AX3) moderate-to-vigorous physical activity. Secondary outcomes include app engagement and retention, quality of life, depression, anxiety, stress, sitting time, sleep, workplace productivity, absenteeism,
presenteeism and habit strength.
The trial presents a unique opportunity to study the effectiveness of a new generation of digital interventions that use advanced machine learning methods to improve physical activity behaviour. By addressing the limitations of existing conversational agents, we aim to pave the way for more effective and adaptable interventions.
Trial registration Australian New Zealand Clinical Trial Registry ACTRN12624000255583p. Registered on 14 March
A Time for Thinking 